MDDT LAD access procedure:
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Contact [email protected] with an initial request for an LAD MDDT performance report.
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We will establish the appropriate pricing tier, set up a UCSF material transfer agreement and contract/invoice.
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You will send us an executable that is set up to process one MIT-formatted ECG record at a time and produces an output alerts file for that record.
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CBR personnel will run your executable across all LAD records and calculate overall performance metrics, summarized in a final report.
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You receive the final LAD MDDT report. We will delete your executable from our system after you confirm receipt.
FAQs:
Can I access the recordings and annotations directly?
The 19 months of data qualified by the MDDT cannot be used for algorithm development, whether by industry professionals or academic researchers, and as such will not be shared. Once a contract is set up, sample data can be provided to demonstrate data formatting for developing your executable.
What is the expected input and output format of the data for algorithm testing?
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The inputs are stored in MIT format (see 2.1), so each record has one header file (.hea) and one file containing all waveforms (.dat).
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The output is expected as a csv file, where each row has 3 columns: the alarm label (VT, AS, VF), the alarm start time, and the alarm end time, i.e. “VT,5/2/2014 12:11:16 AM,5/2/2014 12:15:36 AM”
How much does a report cost?
We have several price tiers depending on the type of report requested and the requesting entity. Please contact us for a quote for your specific needs.
What is included in the report?
See the FDA documentation here. Briefly, performance metrics are calculated for each arrhythmia individually and combined. They are based on sensitivity and positive predictivity and include the numbers of false positives and false negatives. Those results are reported in aggregate and subset by categories such as ICU, Age, Gender, Day, and Subject, and on a record-by-record basis (for the full report).
How do I know my method’s false positives are really false positives?
The LAD underwent a rigorous annotation process as described in the FDA documentation. The LAD undergoes ongoing quality assessments at regular intervals. Updates to the database due to re-annotated events will be communicated to the FDA.
Where can I read more about the annotation process?